It is usually followed by a papular eruption, the individual papules being raised above the surface of the skin, smooth or scaly, and as they are due to infiltration of the skin they are more persistent than the roseoles.
At the anus the papules acquire the characters of condylomata, also at the angles of the mouth, where they often ulcerate and leave radiating scars.
The spirochæte may be recognised in films made by scraping the deeper parts of the primary lesion, from papules on the skin, or from blisters artificially raised on lesions of the skin or on the immediately adjacent portion of healthy skin.
They are papules occurring on those parts of the body where the skin is habitually moist, and especially where two skin surfaces are in contact.
Although all types of skin affection are met with in the inherited disease, the most important is a papular eruption, the papules being of large size, with a smooth shining top and of a reddish-brown colour.
The co-existence of scaly papules and faded roseoles is very suggestive of syphilis.
It causes much irritation, with the eruption of papules or vesicles and the formation of sores and scabs.
The hairs may be broken and rubbed off, but the part is never entirely bald, as in ringworm, and there may be papules or any kind of eruption or open sores from the energy of the scratching.
At the height of the attack the man lost appetite and spirit, had a pricking sensation, and sometimes minute red papules appeared all over the hand.
These become fused into crimson, slightly raised maculae, which in severe cases become further fused into red thickened patches, in which the papules can still be felt and sometimes seen.
It consisted of closely disposed papules of the size of a pin-head, and several days after the disappearance of the eruption a fine, bran-like desquamation of the epidermis ensued.
The front of the chest below the nipples was covered with dark papules the size of a pin's head.
Another year of the same treatment and the fourth spring eruption showed itself slightly only in small papules behind the ears and between the fingers, and were hardly worth noticing.
Little papules on skin, with redness, feeling like nettles; this occurred on the fifth day of the proving.
Eruption of small papuleson a raised base with intolerable itching.
At night she became feverish, hands and face would burn, then intolerable itching followed by erythema with smallpapules becoming pustular.
The subsequent course of the eruption will leave no room for doubt, since within twenty-four hours the papules of smallpox will have developed into characteristic vesicles.
Papules were noticeable on the hands and feet, particularly on the palms.
In the early stage we may see macules changing into papules on the head and the neck, while there are simply macules on the trunk.
He claims that if the lotion is rubbed over the whole body every four or six hours it will prevent the papules from reaching the pustular stage and thus avert the severe secondary fever.
The papules continue to increase slowly in size, the apex becoming flattened or indented in some lesions.
In some parts of the body papules were found which were almost black.
What modifications do the papules of the large-papular syphiloderm sometimes undergo?
In those severe and persistent cases in which excoriations and papules have resulted from the scratching, the history of the case, together with its course, must be considered.
There are no primary structural lesions, but in severe and persistent cases the parts become so irritated by continued scratching that secondary lesions, such as papules and slight thickening and infiltration, may result.
Scattered minute pustules and some large papules are usually present.
In some instances, not more than five or ten papules and pustules are present at one time; in others they may be numerous.
The dry, flatpapules gradually become moist and covered with a grayish, sticky, mucoid secretion; several may coalesce and form large, flat patches.
Sometimes the papules are capped with a small vesicle (vesicular urticaria).
The distribution and extent of the eruption, the color, the grouping, with usually the presence of pustules and large papules and other concomitant symptoms of syphilis, are points of difference.
New papules may appear from time to time, the older lesions disappearing and leaving persistent reddish or brownish pigmentation.
The papules tend, sooner or later, to develop into vesicles, new papular outbreaks occurring from time to time; or the whole eruption changes to the vesicular or other type of the disease.
In some cases, especially in the region of the ankle, the papules become quite large (lichen planus hypertrophicus), and in occasional cases there is a tendency in some of the lesions or patches to clear up centrally.
The papules are elevated and pointed, with a small zone of bright redness of the skin round the base of each.
There is a symmetrical rash of bright red papules on both arms as high as the elbows, more copious and bright on the right arm but abundant on the left also.
Not infrequently the papules are large, and sometimes a few pass into vesicles or pustules.
In measles the papules are very small, mostly confluent, from four to six landing on a single areola, which is larger than that of rötheln.
Minute maculo-papules can be distinguished here and there over the surface, often closely set together, and presenting the characteristic color described above.
In this way the epidermis is raised into the flat solid papules which are the early lesions of the disease.
The latter seems to have fully recognized the characteristics of the eruption, for he says that it consisted of "elevated papules which disappeared completely on pressure.
The papules are dark red and more elevated, are about the size of hempseeds, and situated at the mouths of the hair-follicles.
At any rate, the question will generally settle itself in the next twenty-four hours, for if it be variola the papules will have undergone their specific development and the rubeolous elevations will have become more decidedly macular.
It is certain that the bites of either mosquitoes, fleas, or bedbugs may in this disease be followed by persistent reddish papules passing into petechiæ.
We also noticed an eruption of pale-reddish, slightly elevated papules in seven cases.
This usually appears on the fourth day as small red papules on the forehead, along the line of the hair and on the wrists, spreading within twenty-four hours over the face, extremities, trunk and mucous membrane.
The papules become hollowed vesicles and a clear fluid fills them on the fifth or sixth day.
The rash of measles is a characteristic eruption of rose colored or purple colored papules (pimples).
There is, I believe, something in protecting the ripening papulesfrom the light.
A few new papules are seen on the second day, perhaps a few fresh ones on the third day.
Purpura papulosa (lichen lividus, Willan) is a form of purpura where, in the midst of ecchymoses, livid papules appear.
Or the various formative stages of the pustules may be passed through so quickly that the eruption will be almost entirely pustular, few if any unmodified papules being discovered.
It is contended that the so-called pustules of variolous oesophagitis are really superficial variolous ulcers, the antecedent specific lesions having been lenticular papules merely, with abrasion of the softened epithelial layer.
In prurigo podicis papules appear which itch intensely, and when scratched bleed, the summit of each papule bearing a small black scab.
The above list will hopefully give you a few useful examples demonstrating the appropriate usage of "papules" in a variety of sentences. We hope that you will now be able to make sentences using this word.