This explains why it has been possible to produce antitoxins from toxins which have lost some of their toxic properties, but which have preserved their property of uniting with antitoxic substances.
On mixing the antitoxic serum of these animals in vitro with the red blood-corpuscles of the species furnishing the serum and of the hemolytic serum of eels, it is found that the blood-corpuscles kept quite well.
These writers, and also Calmette, have shown that the blood of venomous serpents becomesantitoxic when heated.
In the vaccinated animal the antitoxin is reproduced, and it is possible to obtain several times, from the vaccinated animals, successive portions of antitoxic serum.
This alone suffices to show that, during physiological life, oxygen plays an essentially antitoxic rôle within the organism.
By immunizing guinea-pigs, rabbits, and horses with this cholera toxin, Metchnikoff and Roux obtained a serum which is distinctlyantitoxic for rabbits.
From the moment that large quantities of blood and antitoxic serum were at command, search was made for a means of isolating the antitoxin and determining its properties.
The immunized animals yield a serum which, mixed with tetanus cultures, renders these innocuous, and which enjoys anantitoxic power that borders on the marvelous.
Metchinkoff[162] has confirmed these facts, and has moreover demonstrated that the blood of the scorpion possesses an undoubted antitoxic power against the poison of the insect.
The antitoxic serum is our sheet-anchor in the treatment of diphtheria, and recourse should be had to its use as early as possible.
To counteract the general effect of toxins absorbed into the circulation, specific antitoxic sera are employed in certain forms of infection, such as diphtheria, streptococcal septicæmia, and tetanus.
The immunity produced by injections of antitoxic sera lasts only for a comparatively short time, seldom longer than a few weeks.
The serum drawn off at each bleeding must be severely tested, which is done by gauging its antitoxic power in vitro, when mixed with venom, and also its preventive effect.
It really seems, therefore, that the resistance of the hedgehog to venom is due to the presence of antitoxic substances in its blood.
It may be asked whether this is due to their blood normally containing antitoxic substances.
After a few hours everything returns to its normal condition, and if the injection of a lethal dose of venom is repeated several times, at intervals of a few days, it is not long before antitoxic substances are found to appear in the serum.
Neutralising, by the injection of a sufficient quantity of antitoxic serum, the effects of the venom already absorbed.
This need not surprise us, since the coagulant substances in venoms are destroyed by heating, and the animals vaccinated in order to obtain antitoxic serum are usually inoculated exclusively with heated venoms.
But it is always difficult to push the vaccination far enough for the serum to acquire antitoxic properties, and I have never been able to prove the appearance of the latter.
Serum prepared in this way preserves itsantitoxic power unimpaired for about two years, in all climates.
Paolo, for the preparation of the antitoxic serum, which is given in exchange for the snakes.
Like them, they are specific; they are also produced in great quantities and excreted into the humors, which they render antitoxic when sufficiently abundant; finally, they are not very sensitive to high temperatures.
In order to confer antitoxic immunity recourse must be had to vaccination by soluble poisons and toxins.
He ascertained that the vaccination of animals by toxins conferred, after a time, antitoxic powers to the blood and humors which contained leucocytes.
Thus antimicrobian immunity and antitoxic immunity constitute in most cases two distinct properties.
This deduction is also supported by the antitoxic immunity which may be conferred on unicellular beings in which the cell alone enters into play.
During antitoxic vaccination, the macrophages manufacture, probably at the expense of vaccinal toxins, a certain quantity of antitoxins, substances which offer a great similarity with the fixators.
Serum from a horse properly immunized against diphtheria toxin; has a potency of not less than 250 antitoxic units per Cc.
Certain antitoxic proteins from the blood serum of a horse properly immunized against diphtheria toxin, dissolved in physiologic solution of sodium chloride.
Certain antitoxic proteins from the serum of a horse properly immunized against tetanus toxin.
We are further of the opinion that in antitoxicserum we possess a remedy of distinctly greater value in the treatment of diphtheria than any other with which we are acquainted.
I am still injecting these two animals with venom, and I hope to give to their serum at last a much greaterantitoxic power.
Bruschettini, Genoa, Italy, is claimed to have the properties “of acting directly on the tubercular bacillus, bringing directly into the field and determining a hyperproduction of antibacillar and antitoxic substances.
Williams suggests that the vitamines have "a general, non-specific, antitoxic or eliminative action" on toxic substances resulting from the metabolic decomposition of food.
The antitoxic theory suffers from the fact that the toxic origin of scurvy cannot be established.
The original diphtheria serum employed was not concentrated; so when a sufficient amount of antitoxic units to neutralize the toxins of the disease under treatment was employed, a large quantity of serum had to be injected.
That is because each of these diseases leaves behind it, on its first appearance, its antitoxic influence.
From which he concluded that the toxic and antitoxic effect of the salts were due to the manner in which its atoms are electrically charged.
In the case of diphtheria the antitoxic power of the serum may reach 800 units per cubic centimetre, or even more.
The antitoxic property is developed in a susceptible animal by successive and gradually increasing doses of the toxin.
These circumstances serve, in part at least, to explain the fact that the success attending the use of anti-bacterial sera has been much inferior to that in the case of antitoxic sera.
Immunity against toxins also became a subject of investigation, and the result was the discovery of the antitoxic action of the serum of animals immunized against tetanus toxin by E.
So far as bacterial immunity is concerned, the anti-serum exerts its action either on the toxin or on the bacterium itself; that is, its action is either antitoxic or anti-bacterial.
The antitoxic serum when injected previously to the toxin also confers immunity (passive) against it; when injected after the toxin it has within certain limits a curative action, though in this case its dose requires to be large.
The above list will hopefully give you a few useful examples demonstrating the appropriate usage of "antitoxic" in a variety of sentences. We hope that you will now be able to make sentences using this word.
