Of the solid tumours the glioma and the sarcoma are the most common, and when they originate in the pigmented structures of the globe they present the characters of melanotic growths.
A still further complication in the composition of melanin is suggested by Kunkel,[46] who has isolated a ferrated pigment from melanotic tumors.
That its nature is similar to the normal pigment of the skin and choroid is suggested by the customary origin of the melanotic tumors in such pigmented tissues, and by the resemblance in appearance and reactions.
The black pigment of the cells of melanotic tumors, also called melanin, is not to be directly traced to the hæmoglobin.
Footnote 79: I have not been able to find an authentic instance of primary melanotic cancer of the stomach, although this form is included by most authors in the list of primary gastric cancers.
So-called melanotic cancers, cancers involving only the serous coat of the stomach, and those extending by continuous growth into the stomach, are not included in this list.
Melanotic sarcoma may occur as metastatic from an original melano-sarcomatous tumor of the skin or eyeball.
Secondary melanotic tumors have been several times found in the stomach.
Of course gastric cancers colored by pigment from old blood-extravasations should not be confounded with melanotic tumors.
It is known that most cases formerly described as melanotic cancers are melanotic sarcomata, which originate usually in the skin or the eye and are accompanied frequently with abundant metastases.
In the case of the melanotic infiltration the whole organ is uniformly enlarged, reaching in a few months the enormous size of twelve to twenty pounds.
Melanin pigment is formed in relation to the cells and stroma of certain epithelial tumours, giving rise to melanotic cancer, one of the most malignant of all new growths.
Diffuse Melanotic Cancer of Lymphatics of Skin secondary to a Growth in the Sole of the Foot.
In addition to being unsightly, they bleed freely when abraded, are liable to ulcerate from friction and pressure, and occasionally become the starting-point of melanotic cancer.
Squamous epithelioma and melanotic cancer are the forms met with.
Melanotic Cancer of Forehead with Metastases in Lymph Vessels and Glands.
There are several types of primary cancer of the skin, the most important being squamous epithelioma, rodent cancer, and melanotic cancer.
The pigmented varieties include the chloroma, which is of a light-green colour, and the melanotic sarcoma, which is brown or black.
In a melanotic eye, which I lately examined with Mr. Dalrymple, there was a part in which the black matter seemed to be contained within the capillary vessels.
The disease mostly occurs in the trunk, seldom in the extremities; it is not uncommon in the orbit, and in the internal organs the melanotic deposits are generally both numerous and extensive.
While paralysis of the femoral nerve, also known as "dropped stifle" occurs as a result of local injuries and melanotic tumors in gray horses, most cases are due to azoturia.
Hip lameness may also be provoked by melanotic or other tumors.
Melanotic tumors in the paraproctal tissue in some cases, because of the large size of the new-growths, cause paralysis of the sciatic nerve.
They were, therefore, usually supposed to belong to the class of melanotic formations, from presenting, as their distinguishing feature, a greater or less degree of blackness.
There exists a marked chemical distinction between the melanotic and the carbonaceous matter; and the anatomical situation of the two is also different.
It is proved, from the difference in the chemical character possessed by the melanotic matter, as compared with the matter found in the lungs of miners.
The melanotic matter is easily effaced by washing, while the other is removed with difficulty.
Eiselt states that he also found melanine in the urine in a case ofmelanotic cancer of the eyeball.
Eiselt of Prague called attention to the fact that in cases of melanoticcancer of the liver, melanine appears in the renal secretion.
This deepening of the colour is no doubt due to the oxidation of the melanotic pigment, as the employment of an oxidizing agent, such as nitric or chromic acid, causes the same change to occur instantly.
Care must be taken not to confound the dark olive-green urine occasionally met with in other forms of jaundice, with the melanotic urine just described, or both {70} patient and doctor may become unnecessarily alarmed.
In jaundice arising from melanotic cancer of the liver, the recognition of the presence of melanine in the urine would be an important aid to the diagnosis.
The above list will hopefully give you a few useful examples demonstrating the appropriate usage of "melanotic" in a variety of sentences. We hope that you will now be able to make sentences using this word.
