Strychnin is a very concentrated poison and produces its effect very quickly, usually only a few minutes being necessary if given in sufficient dose and in such a way that it will be at once absorbed.
Nearly all cases will recover if a hypodermic injection is given immediately of physostigmin salicylate 1 grain, pilocarpin hydrochlorid 2 grains, strychnin sulphate 1/2 grain.
When the next time for their injection came, however, these patients who had been given whiskey on their request did not now receive an injection of strychnin but instead a small injection of apomorphin.
Perhaps the most famous of them, the one whose institutes were found all over the country, was said to have used only two drugs, strychnin and apomorphin.
The strychnin was given as a needed and well-chosen tonic for the physical condition of the patients who came to the institution usually in a rather seriously broken down condition.
Of course, the bitter tonics, especially strychnin and cinchona, will do much to help.
Yet it is asserted that this strychnin salt is of superior value because it combines the effects of strychnin with a “food-like form of phosphorus.
Strontium Salicylate not superior to Sodium Salicylate, 572 Strychnin Arsenate, The Journal, Sept.
These investigations have included a study of the action of strychnin in cardiac disease, a comparison of the action of absorption and excretion of iodid preparations, a study of the pharmacology of the opium alkaloids, etc.
In addition, the federal chemists found that some Elixir of Iron pyrophosphate Quinin andStrychnin (Elix.
Triple Arsenates with Nuclein is said to contain “Strychnin Arsenate gr.
The phosphorus content of 1/64 grain of strychnin glycerophosphate is ridiculously small.
The effects of arsenic and strychninare very different and there are comparatively few conditions in which they should be prescribed at the same time.
He was put on light, nourishing diet, iron and strychnin were given internally, and electricity was applied to the lower extremities every other day; the cystitis was treated by irrigating the bladder each day with Thiersch's solution.
A curious case is mentioned in which three mustard plasters, one on the throat, one on the back of the neck, and another on the left shoulder of a woman, produced symptoms similar to strychnin poisoning.
It could not be ascertained whether any medicine containing strychnin had been taken, but surely, from the symptoms, such must have been the case.
Happily, strychnin was given in time to effect recovery, and without early medical assistance she would undoubtedly have succumbed.
Henning and Ahlfeld, two German observers, vouch for the opinion of Thomas, and Thornburn states that he has witnessed the effect of nux vomica and strychnin on the fetus shortly after birth.
Thornburn believes that the administration of a tonic like strychnin is of benefit to a fetus which, by its feeble heart-beats and movements, is thought to be unhealthy.
Hatcher comes to the conclusion: “Either Myers’ work was a pure fabrication or he was dealing not with cactin but with a substance similar to the pellotin of Heffter, the action of which resembles that of strychnin to a certain extent.
Potent alkaloids such as aconitin, cocain, morphin and strychnin were not found.
Once in six hours is generally often enough forstrychnin to be administered unless the dose is very small.
Strychnin in small doses may be needed, but in these patients, who are generally nervous, it is usually better not to give it.
Strychnin is overused in the cases of most patients who are seriously ill.
Strychnin did not raise either pressure until the dose was sufficient to cause muscular contractions.
The strychnin may be repeated in three, four or five hours, depending on the size of the previous close.
Strychnin may also be given, and digitalis, hypodermically, if it seems indicated.
If such be the fact, strychnin is not acting for good in a patient who has cardiac weakness.
On the other hand, strychnin in the low blood pressure of serious illness, such as pneumonia, by no means always raises the blood pressure.
In a patient in whom we are trying to cause nervous and muscular rest, strychnin is certainly contraindicated.
Strychnin is indicated when the heart is acting sluggishly and the contractions seem incomplete, and when digitalis either is not indicated or is not acting perfectly.
In many instances in which digitalis is contraindicated, strychnin is of marked value.
Sapræmia in these respects, therefore, is comparable to poisoning by any other form of alkaloid, such as strychnin or morphin.
The diet should be liberal and easily digested, and strychnin and other stimulants may be of service.
Cardiac stimulants, such as strychnin or alcohol, must be judiciously administered, over-stimulation being avoided.
In strychnin poisoning, for example, the spasms come on immediately after the patient has taken a toxic dose of the drug; they are clonic in character, but the muscles are relaxed between the fits.
Hypodermic injections of strychnin in doses sufficiently large to produce a slight degree of poisoning by the drug are particularly useful.
Little can be done after the air has actually entered the vein beyond endeavouring to maintain the heart's action by hypodermic injections of ether or strychnin and the application of mustard or hot cloths over the chest.
Indeed, thousands of people have been killed by strychnin poisoning.
Strychnin is quite different in its effects from the above-mentioned alkaloids, for instead of benumbing the nerves, causing sleep or a pleasing sensation, the effect is a nerve stimulus which causes muscular convulsions.
The medical use of strychnin is more of a stimulant than of a narcotic.
The brains of rabbits which had been kept awake for one hundred hours showed precisely the same changes as those shown in physical fatigue, strychnin poisoning, and exhaustion from emotional stimulation.
We have studied the brains of animals which had been activated in varying degrees up to the point of complete exhaustion by running, by fighting, by rage and fear, by physical injury, and by the injection of strychnin (Figs.
After the administration of 5 grams of caffein sodium salicylate by mouth to a dog weighing 10 kilos, he noticed salivation, restlessness, vomiting, and convulsions as in strychnin poisoning.
After injecting from 4 to 20 mg tetanus, such as observed in strychnin poisoning, was noticed.
Cantharadin, phenol, atropin, and strychnin may be mentioned as illustrations.
The effect of caffein produced in the green frog was analogous to that observed in strychnin poisoning.
This is made evident by the action of strychnin on frogs in which, according to Maurel(56), the toxic dose is the same whether given by mouth or injected into the subcutaneous tissues.
This appears to hold true also for other animals as demonstrated by the experiments of Hatcher(35) on the cat, in which he observed that strychnin is as readily absorbed from a full stomach as from the subcutaneous tissues.
Strychnin sirup is prepared as follows: Dissolve a half ounce of strychnia sulphate in a pint of boiling water; add a pint of thick sugar sirup and stir thoroughly.
Strychnin is too rapid in action to make its use for rats desirable in houses, but elsewhere it may be employed effectively.
The dry crystals may be inserted in small pieces of raw meat, Vienna sausage, or toasted cheese, and these placed in rat runs or burrows; or oatmeal may be moistened with a strychnin sirup and small quantities laid in the same way.
This applies particularly to strychnin or arsenic on meat.
Owing to its slower operation, no doubt a larger portion escape into the open before dying than when strychnin is used.
The grain should be soaked overnight in the strychnin sirup.
Local applications, stimulative in character, are beneficial, and the internal administration of strychninis indicated.
In young and vigorous subjects where cause is not definitely known, a course of strychnin may be given.
Good hygienic care, a suitable diet and full physiological doses of strychnin are indicated.
The above list will hopefully give you a few useful examples demonstrating the appropriate usage of "strychnin" in a variety of sentences. We hope that you will now be able to make sentences using this word.
