I once lived in a house terribly infested with rats, and I wanted to get rid of them as quick as I could, for they were a great nuisance.
Paul regarded the unnecessary use of unknown tongues in the assemblies of the Church, as a great nuisance.
Of works of fiction I read very few, and evermore still fewer as I got older, until at length I came to view them generally as a great nuisance.
The subscription packs of foxhounds were also a great nuisance, many of the followers being townsmen who bored through hedges and smashed the gates and stiles, conduct not unknown to-day.
On the great estates these offices tended to become hereditary, and many families did treat them as hereditary property, and were a great nuisance in consequence to their lords.
The landing and all the Customs business was a great nuisance, though we got through capitally.
Then the baggage chequing business turned out a great nuisance, the men went down to cheque it while I was away getting the tickets, and when I came back they had all gone away.
The kites, marabouts, and vultures were a great nuisance.
Although this is a great nuisance (as cutting the throat spoils the head skin), it is right to respect such customs, and I always made a point of killing something else, so that they should not suffer for their belief.
No, he thinks he shall sell out, for the army is a great nuisance.
He asked me if lying here was not a great nuisance, and, at last, he grew tired of twisting his moustache, and went away.
The above list will hopefully provide you with a few useful examples demonstrating the appropriate usage of "great nuisance" in a variety of sentences. We hope that you will now be able to make sentences using this group of words.