A dose of 220 grains may be considered a large dose.
Cocoa or chocolate is a vehicle in which a large dose might be given.
It would be very difficult to give a large dose in a liquid.
In a case recorded by Christison,[120] death occurred in four minutes from a large dose, doubtless partly by suffocation.
In a case related by Orfila, there was even a small perforation by a large dose of potassic nitrate, and a remarkable preservation of the body was noted.
Swallowing a piece of ice will sometimes produce pain over the brow; and it is likely that the headache which follows over-eating, or a large dose of a tonic medicine, may result in a similar way from mere irritation of the stomach.
So a large dose of Turpentine or Cantharides may cause a dangerous attack of strangury, or even a total suppression of the urine for a time.
It should be observed, that the irritant action on the stomach of a large dose of a bitter medicine appears to have been the chief foundation of this frequent opinion of the stimulant action of tonics.
In the same way we find that a large dose of Mercury, naturally a Cholagogue, may produce jaundice, by causing congestion of the liver.
The action usually lasted from two to six hours, and quite a large dose was at length necessary.
Bremuse gives an account of a man who literally split his diaphragm in two by the ingestion of four plates of potato soup, numerous cups of tea and milk, followed by a large dose of sodium bicarbonate to aid digestion.
Harley says that the fakirs begin their performances by taking a large dose of the powerfully stupefying "bang," thus becoming narcotized.
As it was impossible to bring him into anything like a hypnotic condition by ordinary means, a large dose of chloral was administered.
It then became their custom to take a large dose of epsom salts on Saturday night and spend most of the day on Sunday getting rid of the accumulated excrementitious material of the whole week.
When a large dose of opium or its tincture has been taken the symptoms usually manifest themselves in about twenty or thirty minutes.
Sometimes this same eruption appears in the throat and on the skin after swallowing a large dose.
Although not a powerful irritant, sulphate of iron has proved fatal when taken in a large dose.
The above list will hopefully provide you with a few useful examples demonstrating the appropriate usage of "large dose" in a variety of sentences. We hope that you will now be able to make sentences using this group of words.
